Publications on Separations and Electrophoresis
Electrophoresis has evolved to become the most important single analytical process in biochemistry, but for preparative work chromatography is more useful. That discrepancy led to a wide range of experimental and theoretical developments.
There is common ground, intellectually, with ideas on selectivity but these papers are best listed in a different category. To a large extent, the history of biochemistry in the 20th century was that of separating out the components of extremely complex mixtures to allow independent study. An engine works as a whole but only because each cog was designed and made to fit perfectly with the other moving parts: to make a difference we need both the big picture and the detail.
S.A. Saeed and T.R.C. Boyde, Purification of antibodies labelled with monomeric ferritin, and their use in the localisation of Salmonella flagellar antigens. Med Sci Res 21 (1993) 817-8 (1993) 817-8
K.Y. To and T.R.C. Boyde, Pulsed-field acceleration: The electrophoretic behaviour of large spherical particles in agarose gels. Electrophoresis 14 (1993) 597-600
S.A. Saeed and T.R.C. Boyde, Large-scale preparative electrophoresis. Laboratory Practice 40 (1991) 77-9
with K.Y. To, The low-molecular weight constituents present after polymerisation of acrylamide in solution. American Electrophoresis Society Meeting, Washington, July 5-11 1989. Abstracts 131.
with K.Y. To, Low-molecular weight constituents of polyacrylamide gels and solutions.Electrophoresis Forum, Munich, October 23-25 1989. Abstracts 340-4
L.S. Cornish Y. Chung, C.S. Ng and T.R.C. Boyde, A microcontroller-based flat bed preparative electrophoresis apparatus. Laboratory Practice 36 (1987) 35-7
Physical basis of haemoglobin behaviour on agar electrophoresis, 16th FEBS Meeting, Moscow (1984) Abstracts p.323, poster XIV-58
S.A. Saeed and T.R.C. Boyde, Horse spleen ferritin: a change of crystal form during crystallisation of monomer is associated with the appearance of oligomers. FEBS Lett 123 (1981) 111-4
S.A. Saeed and T.R.C. Boyde, Preparative electrophoresis at high sample load. The effect of some experimental variables on separation performance. Preparative Biochemistry 10 (1980) 445-62
A critical approach to Separations theory through the "contaminant ratio" concept, with a note on optimum separation. Separation Science and Technology 14 (1979) 79-106 14 (1979) 79-106